In a recreational setting, the dissociative anesthetic properties cause psychotic symptoms of being disconnected from reality – this can range from feelings of utter bliss for some to severe anxiety for others. Ketamine can also have hallucinogenic effects, as it has some similar properties to phencyclidine (PCP), although far less potent. The euphoric feelings described are often where the potential for addiction lies when users look to self-medicate feelings of depression with ketamine without treating the root causes. This leads to a cycle of addiction where someone feels like they need ketamine to cope with social situations or daily life.
Ketamine’s effects depend on the user’s surroundings, unique physiology, and interactions with other drugs. In very high doses, users may report a total out-of-body experience or a k-hole, where they cannot interact with their surroundings at all.
Ketamine also frequently causes memory loss and difficulty moving, so it may be used as a date rape drug.
Users may have dilated pupils, sweating, and poor motor skills while under the influence.
In medical procedures, the effects of ketamine are sedation, temporary pain relief, and relief of depression. The risk of addiction is mitigated when ketamine is used under the supervision of a medical professional, as they will monitor the patient and work with them on the root causes of their symptoms. With a controlled dose and environment, the effects of extreme anxiety are unlikely to happen.